Biological Agents | Infection Control

Employees can be affected in various ways by biological hazards. The Federal Institute for Occupational Safety and Health (Bundesanstalt für Arbeitsschutz und Arbeitsmedizin, BAuA) contributes to the formulation of technical rules for activities involving biological agents. It also develops new measurement methodologies and researches health risks and appropriate protective measures.

Employees in protective clothing in the laboratory
© iStock | RyanKing

Essentially, a risk is present as soon as an activity requires the handling of biological agents, for instance in laboratories, the healthcare sector, veterinary facilities, or the waste management industry.

Natural outbreaks of infectious diseases, sometimes on a pandemic scale, can raise the risk of infection among employees performing many different kinds of activity as well. Other biological agents may not be infectious, but can trigger sensitising or toxic reactions.

In order to ensure employees working with biological agents benefit from cutting-edge protection, our experts on the Committee on Biological Agents (Ausschuss für Biologische Arbeitsstoffe, ABAS) help keep the Technical Rules for Biological Agents (Technische Regeln für Biologische Arbeitsstoffe, TRBAs) up to date. Researchers at BAuA develop new measurement methodologies and assessment tools. Furthermore, they conduct systematic field research into bioaerosols in the workplace with the aim of preventing airborne transmission. And BAuA is preparing for future pandemics by researching both work-related infection risks and suitable protective measures.

It is hoped the results will enable organisations to correctly assess the risks to their employees from biological agents and infectious diseases, then take suitable protective measures, putting in place appropriate plans and precautions for every eventuality.

Research Projects

ProjektnummerF 2584 StatusLaufendes Projekt Consideration of humans as a bioaerosol source for infection control in the workplace - Quantification of proteins in exhaled air

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ProjektnummerF 2583 StatusLaufendes Projekt Investigation of the size distribution of exhaled particles in temporal relation to mask use

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ProjektnummerF 2562 StatusLaufendes Projekt Occupational COVID-19 exposure and infection risks: Analyses based on the Gutenberg COVID-19 Study.

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ProjektnummerF 2545 StatusAbgeschlossenes Projekt Work related investigation of the rate of SARS-CoV-2 infected and Post-COVID symptomatic people based on data of the health authorities in Thuringia

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ProjektnummerF 2547 StatusLaufendes Projekt Determination of exposure during phage application in pig barns

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ProjektnummerF 2546 StatusLaufendes Projekt Characterisation of bioaerosols in the fine dust fraction of indoor air

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ProjektnummerF 2509 StatusLaufendes Projekt Relative quantification of proteins in cell culture system exposed to biological agents by mass spectrometry

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ProjektnummerF 2491 StatusLaufendes Projekt Assessment and evaluation of the toxic potential of biological agents on the basis of respiratory tract-related in vitro models: Subproject II: Development of an exposure system for the assessment of volatile metabolites of biological agents

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ProjektnummerF 2489 StatusAbgeschlossenes Projekt Assessment of health effects by bioaerosols in case of mould

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ProjektnummerF 2486 StatusLaufendes Projekt Determination of the inhalative exposure to biological agents during the commercial use of gardening devices

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ProjektnummerF 2470 StatusAbgeschlossenes Projekt Biomonitoring of workers´ exposure to mycotoxins

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ProjektnummerF 2441 StatusAbgeschlossenes Projekt Analysis of bioaerosol-borne toxins by proteomics technologies

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ProjektnummerF 2426 StatusAbgeschlossenes Projekt Molecular differentiation of living and dead biological agents and detection of the tenacity of airborne biological agents

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ProjektnummerF 2383 StatusAbgeschlossenes Projekt Detection of airborne biological agents under difficult analytical conditions - background measurement and exclusion of inhibitory substances

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ProjektnummerF 2356 StatusAbgeschlossenes Projekt Exposure of hatchery workers to airborne bacteria under consideration of existing antibiotic resistances

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ProjektnummerF 2350 StatusAbgeschlossenes Projekt A model system of lung cells for investigation of bacterial pathogenicity

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ProjektnummerF 2331 StatusAbgeschlossenes Projekt Antibiotic-resistant bacteria in emissions from the industrial livestock farming

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ProjektnummerF 2330 StatusAbgeschlossenes Projekt Exposure to biological agents at biogas production

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Publications

SARS-CoV-2 infection risk by non-healthcare occupations: a systematic review and meta-analysis

Essay 2025

Background: During the COVID-19 pandemic, several industries were deemed essential. However, information on infection risk in …

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A German job exposure matrix for COVID-19 infections (COVID-19-JEM) based on data from the Gutenberg COVID-19 Study (GCS)

Essay 2024

The complete article "A German job exposure matrix for COVID-19 infections (COVID-19-JEM) based on data from the Gutenberg …

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CRISPR/Cas9 gene targeting plus nanopore DNA sequencing with the plasmid pBR322 in the classroom

Essay 2024

Both nanopore-based DNA sequencing and CRISPR/Cas-based gene editing represent groundbreaking innovations in molecular biology …

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(In)equality at the workplace? Differences in occupational safety and health measures during the COVID-19 pandemic and related employee health

Essay 2023

The complete article "(In)equality at the workplace? Differences in occupational safety and health measures during the COVID-19 …

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Authors' response: Occupation and SARS-CoV-2 infection risk among workers during the first pandemic wave in Germany: potential for bias

Essay 2022

This article is published in the "Scandinavian Journal of Work, Environment and Health" (2022).

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BAuA recommendations for action on SARS-CoV-2

baua: Focus 2022

The BAuA recommendations for action on SARS-CoV-2 are intended to provide guidance on when infection protection measures should …

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In Vitro Systems for Toxicity Evaluation of Microbial Volatile Organic Compounds on Humans: Current Status and Trends

Essay 2022

Microbial volatile organic compounds (mVOC) are metabolic products and by-products of bacteria and fungi. They play an important …

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Increases in health problems during the first pandemic wave - An analysis of occupational differences based on the German National Cohort (NAKO)

Essay 2022

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Increases in health problems during the first pandemic wave - An analysis of occupational differences based on the German National Cohort (NAKO)

Essay 2022

The complete article "Increases in health problems during the first pandemic wave - An analysis of occupational differences …

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Occupation and SARS-CoV-2 infection risk among 108 960 workers during the first pandemic wave in Germany

Essay 2022

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